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stem cell markers

NOX4 Regulates TGFβ-Induced Proliferation and Self-Renewal in Glioblastoma Stem Cells

[Molecular Oncology] The glioblastoma tumoral mass was characterized by a small cellular subpopulation, glioblastoma stem cells that has been held responsible for glioblastoma initiation, cell invasion, proliferation, relapse and resistance to chemo and radiotherapy.

MSC-Derived Extracellular Vesicle-Delivered L-PGDS Inhibit Gastric Cancer Progression by Suppressing Cancer Cell Stemness and STAT3 Phosphorylation

[Stem Cells International] Researchers explored whether Mesenchymal stem cell- (MSC-) derived extracellular vesicles-delivered lipocalin-type prostaglandin D2 synthase (L-PGDS) could inhibit gastric cancer progression.

Notch Pathway Inhibition Mediated by Arsenic Trioxide Depletes Tumor Initiating Cells in Small Cell Lung Cancer

[Molecular Biology Reports] Researchers demonstrated that As2O3 had a remarkable inhibitory effect on tumor initiating cells of small cell lung cancer both in vitro and in vivo, and the mechanism might have involved the down-regulation of Notch pathway

CRISPR/Cas9 Editing of Directly Reprogrammed Myogenic Progenitors Restores Dystrophin Expression in a Mouse Model of Muscular Dystrophy

[Stem Cell Reports] Scientists reported on reprogramming of fibroblasts from two Duchenne muscular dystrophy mouse models into induced myogenic progenitor cells by MyoD overexpression in concert with small molecule treatment.

Functional Assessment of miR-1291 in Colon Cancer Cells

[International Journal of Oncology] The expression and effect of miR‑1291 in colorectal cancer cells (CRC) was investigated. It was identified that miR‑1291 significantly suppressed the proliferation, invasion, cell mobility and colony formation of CRC cells.

Sox-Positive Cell Population in the Adult Cerebellum Increases upon Tissue Degeneration

[Experimental Neurology] A Bergmann glia population was analyzed in the adult cerebellum of different species and showed conservation of neural stem cell-associated marker expression including Sox1, Sox2 and Sox9, in chick, primate and mouse cerebellum tissue.

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