stroke

[electroCore, Inc.] electroCore, Inc. announced that the United States Patent and Trademark Office has issued US Patent No. 11,191,953 to the Company, relating to the treatment of stroke symptoms. The newly issued patent is related to methods for treating the acute symptoms of stroke or transient ischemic attack.

[Cell Death Discovery] The co-culture of endothelial cells with CRTC1-deficient neurons aggravated the cell vulnerability to hypoxia, also supporting the idea that miRNA-132/212 cluster was regulated by CRTC1 and acted as a crucial role in the mitigation of ischemic damage.

[Stem Cells Translational Medicine] Dr. Sara Palma-Tortosa is the 2021 recipient of the STEM CELLS Translational Medicine (SCTM) Young Investigator Award. The award honors a young researcher who served as the principal author of an article published in SCTM that, over the course of a year, is deemed to have the most impact.

[Nature Communications] Utilizing single-nuclei transcriptomics to characterize astrocytes after ischemic stroke in the visual cortex of the marmoset monkey, researchers observed nearly complete segregation between stroke and control astrocyte clusters.

[Stem Cells International] Mesenchymal stem cell (MSC) transplantation therapy, which can trigger neuronal regeneration and repair, has been considered as a significant advance in treatment of ischemic stroke.

[Trends in Biotechnology] The authors suggest that a better understanding of human host stroke tissue–hydrogel interactions in addition to the effects of scaling up hydrogel volume to human-sized cavities would help guide the translation of second-generation regenerative stroke therapies.