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TNF-α

Glyphosate-Based Herbicides Induces Autophagy in IPEC-J2 Cells and the Intervention of N-acetylcysteine

[Environmental Toxicology] Researchers investigated the effects of glyphosate-based herbicides on antioxidant capacity, inflammatory cytokines, and autophagy of porcine intestinal epithelial cells IPEC-J2 and its molecular mechanism.

Specific Inflammatory Osteoclast Precursors Induced during Chronic Inflammation Give Rise to Highly Active Osteoclasts Associated with Inflammatory Bone Loss

[Bone Research] Scientists identified TNF-α and S100A8/A9 proteins as key regulators that control the inflammatory osteoclast precursor response during chronic inflammation.

Lipidomic Profiling of Bronchoalveolar Lavage Fluid Extracellular Vesicles Indicates Their Involvement in Lipopolysaccharide-Induced Acute Lung Injury

[Journal of innate Immunity] Extracellular vesicles released during acute lung injury originated from alveolar epithelial cells, macrophages, and neutrophils and carry a diverse array of lipid mediators derived from ω-3 and ω-6 polyunsaturated fatty acids.

Tim-3 Expression Causes NK Cell Dysfunction in Type 2 Diabetes Patients

[Frontiers in Immunology] Scientists compared surface receptor expression and cytokine production between peripheral blood NK cells from 90 Type 2 diabetes mellitus patients and 62 age- and sex-matched healthy controls.

Transplantation of Umbilical Cord Blood-Derived Mesenchymal Stem Cells as Therapy for Adriamycin Induced-Cardiomyopathy

[Bioengineered] Scientists studied the therapeutic effects of umbilical cord blood-derived mesenchymal stem cells transplantation on adriamycin-induced cardiomyopathy.

Cathelicidin Mediates an Anti-Inflammatory Role of Active Vitamin D (Calcitriol) During M. paratuberculosis Infection

[Frontiers in Cellular and infection Microbiology] Scientists examined the role of vitamin D deficiency in the regulation of cathelicidin antimicrobial peptide in Crohn’s disease (CD)-like macrophages, including those infected with Mycobacterium avium subsp. paratuberculosis isolated from CD patients.

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