tuberculosis

[BMC Pulmonary Medicine] Investigators analyzed the cytopathologic characteristics of bronchoalveolar lavage fluid in the diagnosis of HIV/AIDS-related lung disease and compared the lung disease spectrum between HIV and HIV-uninfected patients.

[Nature] A group of international respiratory societies has banned researchers associated with tobacco companies from publishing papers in their journals after the controversial acquisition of a health-care firm that makes inhalers by a tobacco giant.

[American Journal of Pathology] Poorly formed necrotic tuberculosis (TB) granulomas containing a high expression of Mycobacterium tuberculosis antigens were elevated in TB/HIV co-infected lymph nodes, and inducible nitric oxide synthase as well as Arg-1 expression was significantly higher in TB/HIV co-infected compared to HIV-negative TB or control tissues.

[Current Opinion in infectious Diseases] Scientists review the most recent evidences concerning mycobacterial skin infections, limiting the period of literature research to 2020–2021.

[Journal of Experimental Medicine] Using single-cell transcriptomics and T cell receptor sequencing, scientists analyzed mononuclear cell populations in paired pleural fluid and peripheral blood of tuberculous pleural effusion patients.

[Nature Communications] Scientists showed CD1b-mycolipid tetramers revealed a hierarchy in which circulating T cells expressing CD4 or CD8 co-receptor stain with a higher tetramer mean fluorescence intensity than CD4-CD8- T cells.