Tag results:
type I diabetes
Endothelial Cell News
VEGF-A, PDGF-BB and HB-EGF Engineered for Promiscuous Super Affinity to the Extracellular Matrix Improve Wound Healing in a Model of Type 1 Diabetes
[NPJ Regenerative Medicine] In the type 1 diabetic NOD mouse model, engineered growth factors improved both re-epithelialization and granulation tissue formation.
Cell Therapy News
CRISPR Therapeutics and ViaCyte, Inc. to Start Clinical Trial of the First Gene-Edited Cell Replacement Therapy for Treatment of Type 1 Diabetes
[CRISPR Therapeutics, Inc.] CRISPR Therapeutics,Inc. and ViaCyte, Inc., announced that Health Canada has approved the companies’ Clinical Trial Application for VCTX210, an allogeneic, gene-edited, immune-evasive, stem cell-derived therapy for the treatment of type 1 diabetes. Initiation of patient enrollment is expected by year-end.
Immune Regulation News
Diabetes Research Connection Awards $400,000 to Eight Promising T1D Studies as Nation Observes National Diabetes Month
[Diabetes Research Connection (Business Wire, Inc.)] Diabetes Research Connection has provided funds were provided to seven researchers totaling a $400,000 investment aimed at prevention, cure, and better care for those with Type 1 Diabetes .
ESC & iPSC News
Use of Induced Pluripotent Stem Cells to Build Isogenic Systems and Investigate Type 1 Diabetes
[Frontiers in Endocrinology] The authors differentiated iPSC from one donor into dendritic cells, macrophages, endothelial cells, and β-cells, and engineered T cell avatars from the same donor to provide an in vitro platform to study genetic influences on critical cellular interactions.
Pancreatic Cell News
SymbioCellTech Demonstrates Preclinical Efficacy of Proprietary and Novel Human Neo-Islets™ Technology in STZ-Diabetic NOD-SCID Mice
[SymbioCellTech (GlobeNewswire, Inc.)] SymbioCellTech announced the publication of a paper demonstrating the potency and efficacy of its innovative and proprietary human Neo-Islet™ in a third, clinically relevant model of human Type 1 Diabetes.
Pancreatic Cell News
Provention Bio Announces Positive Interim Results from First-in-Human Study of Coxsackievirus B Vaccine Candidate PRV-101
[Provention Bio, Inc.] Provention Bio, Inc. announced positive interim results from PROVENT, a first-in-human study of PRV-101, a polyvalent inactivated coxsackievirus B vaccine candidate targeting all five key CVB strains associated with type 1 diabetes autoimmunity.