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type I diabetes

VEGF-A, PDGF-BB and HB-EGF Engineered for Promiscuous Super Affinity to the Extracellular Matrix Improve Wound Healing in a Model of Type 1 Diabetes

[NPJ Regenerative Medicine] In the type 1 diabetic NOD mouse model, engineered growth factors improved both re-epithelialization and granulation tissue formation.

CRISPR Therapeutics and ViaCyte, Inc. to Start Clinical Trial of the First Gene-Edited Cell Replacement Therapy for Treatment of Type 1 Diabetes

[CRISPR Therapeutics, Inc.] CRISPR Therapeutics,Inc. and ViaCyte, Inc., announced that Health Canada has approved the companies’ Clinical Trial Application for VCTX210, an allogeneic, gene-edited, immune-evasive, stem cell-derived therapy for the treatment of type 1 diabetes. Initiation of patient enrollment is expected by year-end.

Diabetes Research Connection Awards $400,000 to Eight Promising T1D Studies as Nation Observes National Diabetes Month

[Diabetes Research Connection (Business Wire, Inc.)] Diabetes Research Connection has provided funds were provided to seven researchers totaling a $400,000 investment aimed at prevention, cure, and better care for those with Type 1 Diabetes .

Use of Induced Pluripotent Stem Cells to Build Isogenic Systems and Investigate Type 1 Diabetes

[Frontiers in Endocrinology] The authors differentiated iPSC from one donor into dendritic cells, macrophages, endothelial cells, and β-cells, and engineered T cell avatars from the same donor to provide an in vitro platform to study genetic influences on critical cellular interactions.

SymbioCellTech Demonstrates Preclinical Efficacy of Proprietary and Novel Human Neo-Islets™ Technology in STZ-Diabetic NOD-SCID Mice

[SymbioCellTech (GlobeNewswire, Inc.)] SymbioCellTech announced the publication of a paper demonstrating the potency and efficacy of its innovative and proprietary human Neo-Islet™ in a third, clinically relevant model of human Type 1 Diabetes.

Provention Bio Announces Positive Interim Results from First-in-Human Study of Coxsackievirus B Vaccine Candidate PRV-101

[Provention Bio, Inc.] Provention Bio, Inc. announced positive interim results from PROVENT, a first-in-human study of PRV-101, a polyvalent inactivated coxsackievirus B vaccine candidate targeting all five key CVB strains associated with type 1 diabetes autoimmunity.

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