Publication

[Life Science Alliance] Investigators developed a model of the aberrant epithelial reprogramming observed in idiopathic pulmonary fibrosis using alveolar organoids derived from human-iPSCs stimulated with a cocktail of pro-fibrotic and inflammatory cytokines.

[Elife] The authors presented a scalable method for high-throughput screening of cell-free DNA from cardiac organoids.

[Nature] The authors modeled occult preneoplasia by biallelic inactivation of TP53, a common early event in gastric cancer, in human gastric organoids.

[BMC Cancer] Investigators established murine malignant mesothelioma organoids from p53+/- or wild-type C57BL/6 strain by intraperitoneal injection either with crocidolite or carbon nanotube.

[Biofabrication] Researchers detailed an advanced vascularized lung cancer model, which includes patient-derived lung cancer organoids, lung fibroblasts, and perfusable vessels using 3D bioprinting technology.

[Nature Communications] Researchers screened the lysyl-oxidase family to clarify its contribution to chemotherapy resistance in liver cancer.