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Common Fragrance Chemicals Activate Dendritic Cells in Coculture with Keratinocytes

[Contact Dermatitis] To evaluate the 2D coculture model consisting of keratinocytes and dendritic cells, different weak to moderate sensitizing fragrance chemicals were tested in the coculture activation test, consisting of HaCaT keratinocytes and THP-1 cells.

Design and Characterization of Adipose-Derived Mesenchymal Stem Cell Loaded Alginate/Pullulan/Hyaluronic Acid Hydrogel Scaffold for Wound Healing Applications

[International Journal of Biological Macromolecules] In in vitro studies, cells could be attached, alive, and migrate through the prepared hydrogel scaffold. The therapeutic effect of the cell-seeded hydrogels was tested in the full-thickness animal wound model.

A Chronic Wound Model to Investigate Skin Cellular Senescence

[Aging-Us] The authors described a chronic wound murine model and its cellular senescence profile, including the senescence-associated secretory phenotype.

Design, Optimization and Characterization of a Novel Antibacterial Chitosan-Based Hydrogel Dressing for Promoting Blood Coagulation and Full-Thickness Wound Healing: A Biochemical and Biophysical Study

[International Journal of Biological Macromolecules] Cell studies showed biocompatibility and non-toxicity of the hydrogel along with the promotion of cell migration, and the in vivo data revealed enhanced tissue regeneration and recovery within 17 days in the studied animals.

Neuropeptide Y Promotes the Treatment of Adipose Stem Cells on Type 2 Diabetic Wounds

[Tissue Engineering And Regenerative Medicine] Scientists investigated the effects of neuropeptide Y (NPY) on adipose-derived stem cells (ASCs) proliferation and growth factors expression and secretion, the effects of NPY on skin fibroblasts, and the effects of NPY combined with ASCs on Type 2 diabetes wound healing.

MicroRNA-708 Emerges as a Potential Candidate to Target Undruggable NRAS

[PLOS One] Overexpression of miRNA-708 successfully reduced NRAS protein levels in melanoma, leukemia, and lung cancer cell lines with NRAS mutations, resulting in suppressed cell proliferation, anchorage-independent growth, and promotion of reactive oxygen species-induced apoptosis.

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