Publication

[NPJ Vaccines] Researchers evaluated the immunogenicity and efficacy of different rationally designed lipid and polymeric-based nanoparticle prototypes against SARS-CoV-2 infection.

[BMC Pulmonary Medicine] Investigators explored whether small airway inflammation was the risk for the development of COPD.

[Archives Of Toxicology] The authors investigated the expression and functional role of YES1, one of the Src-family kinases, in epidermal growth factor receptor(EGFR)-TKI-resistant NSCLC. YES1 expression was elevated in gefitinib-resistant HCC827 cells, harboring EGFR mutations.

[Science Signaling] Scientists demonstrated that eEF1A2 exhibited oncogenic or tumor-suppressor functions depending on its interaction with METTL13 or the phosphatase PTEN, respectively.

[Cell Death & Disease] Researchers proposed the therapeutic efficacy and molecular mechanism underlying RC48, a FDA-approved anti human epidermal growth factor receptor 2 (HER2) antibody conjugate via a cleavable linker to the microtubule inhibitor monomethyl auristatin E, either alone or in combination with gemcitabine in various models of HER2-positive advanced colorectal cancer.

[Cellular & Molecular Biology Letters] Investigators defined the loss of miR-101-3p expression in melanoma cells compared with melanocytes and melanoblast-related cells as an early event in tumor development and aimed to understand the tumor suppressive role of miR-101-3p and its regulation of important cellular processes.