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Mesenchymal Stem Cells Inhibit Ferroptosis by Activating the Nrf2 Antioxidation Pathway in Severe Acute Pancreatitis-Associated Acute Lung Injury

[European Journal Of Pharmacology] Scientists investigated the protective effects of MSCs against aevere acute pancreatitis-associated acute lung injury and its underlying mechanisms. Their results suggest that MSCs mitigate pathological injury, hemorrhage, edema, inflammatory response in lung tissue, and lipopolysaccharide-induced cell damage in RLE-6TN cells.

Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Pretreated by Monosialoteterahexosyl Ganglioside Alleviate Intracerebral Hemorrhage by Down-Regulating Autophagy

[Experimental Cell Research] In vitro, human umbilical cord mesenchymal stem cells were cultured and induced to differentiate into neuron-like cells after they were pretreated with 150 μg/mL monosialoteterahexosyl ganglioside.

Mesenchymal Stromal/Stem Cells (MSCs) Know Best: The Remarkable Complexities of Its Interactions with Polymorphonuclear Neutrophils (PMNs)

[Stem Cells] Researchers highlighted the intricate interplay between PMNs and MSCs and their profound relevance in healthy and pathological conditions, shedding light on how to best strategize the use of MSCs in the expanding list of diseases with PMN involvement.

Superoxide Dismutase 2 Promotes the Immunosuppressive Function of Mesenchymal Stem Cells at the Expense of Adipocyte Differentiation

[Molecular Therapy] Investigators demonstrated that the adipocyte differentiation and immunomodulatory function of human adipose tissue derived MSCs are mutually exclusive.

Dynamic Tracking of Human Umbilical Cord Mesenchymal Stem Cells (hUC-MSCs) Following Intravenous Administration in Mice Model

[Regenerative Therapy] Scientists investigated the biodistribution, homing and clearance of systemically administered human umbilical cord-MSCs in healthy BALB/c mice model.

Exosomes Derived from Umbilical Cord Mesenchymal Stem Cells Ameliorate Male Infertility Caused by Busulfan In Vivo and In Vitro

[Ecotoxicology And Environmental Safety] Investigators explored the functional restoration and mechanism of Human umbilical cord MSC exosomes on busulfan-induced injury in GC-1 spg cells and ICR mouse testes.

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