Publication

[Nature Communications] Researchers used combined transcriptomic data derived from peripheral blood mononuclear cells of heart failure patients, both with and without CHIP, and cardiac tissue.

[EMBO Journal] The authors investigated the functional involvement of MITOL in HSC maintenance by generating MX1-cre inducible Mitol knockout mice.

[Nature Structural & Molecular Biology] Researchers investigated the transcription factors regulomes during the first lineage specification in early mouse embryos, spanning the pre-initiation, initiation, commitment, and maintenance phases.

[Cell] Scientists developed a bispecific DC-T cell engager, a reagent that facilitated physical interactions between PD-1+ T cells and conventional type I dendritic cells.

[EMBO Molecular Medicine] In immunocompetent mice, intraperitoneal administration of IL-33 could induce a celiac inflammatory environment, activated immunologic effector cells, and reverse the immunosuppressive tumor microenvironment, which effectively delayed tumor progression and peritoneal metastasis of gastric cancer.

[eLife] Scientists developed a novel and versatile immune monitoring strategy by adding a short cysteine-rich tag to antigenic peptides that emited fluorescence upon binding to thiol-reactive biarsenical hairpin compounds.