Publication

[Glia] Microglia were successfully differentiated from retinoblastoma patient- derived human induced pluripotent stem cells and human embryonic stem cells, and investigated the function of RB1 in microglia by live imaging phagocytosis assay, immunofluorescence, RNA-seq, qRT-PCR, ELISA and retina organoids/microglia co-culturing.

[Proceedings Of The National Academy Of Sciences Of The United States Of America] Scientists performed an unbiased proteomic analysis and identified a fibronectin-derived peptide called Anastellin that was unique to the tissue inhibitor of metalloproteinase-1 (TIMP1) knockout astrocyte secretome.

[Nature Communications] The authors conceived a series of lipid nanoparticles to reprogram sdipose stem cells with durable protein secretion capacity for enhanced tissue engineering and regeneration

[ACS Nano] Scientists demonstrated that the assembled RNA-OG-peptide nanovaccines induced dendritic cell maturation, reduced tumor-mediated immunosuppression, and mobilized tumor-specific CD8+ T cell responses at the tumor site.

[Journal Of Thrombosis And Haemostasis] Researchers investigated the breast tumor coagulome and its relation to prognosis, treatment response to chemotherapy, and the tumor microenvironment.

[International Journal Of Oncology] A combination of an androgen receptor (AR) inhibitor and a selective histone deacetylase inhibitor was used to treat AR‑positive TNBC cell lines, and a synergistic effect of these drugs was observed.