Publication

[Neuron] The authors showed that Alzheimer's disease pathologies flipped interactions between the default mode network and the medial temporal lobe from inhibitory to excitatory.

[Cell Reports] Microglial lineage tracing revealed that both microglia and monocyte-derived macrophages initially accumulated, but microglia later dominated the lesion during remyelination in multiple sclerosis.

[Molecular Neurodegeneration] TCRAβ -Tregs were generated by CRISPR-Cas9 knockout of endogenous T cell receptor (TCR) and consequent incorporation of the transgenic TCRAb identified from amyloid-beta (Aβ) reactive Teff monoclones.

[Cell Death Discovery] Scientists investigated the impact of MALT1 inhibition by MI-2 on the functions of vascular smooth muscle cells, both in vitro and in vivo.

[Cell Death & Disease] Investigators used bioinformatic approaches, machine learning algorithms, systems biology analyses, and statistical techniques to define co-expression modules linked to heart development and cardiovascular diseases.

[Science Immunology] The authors profiled human embryonic and fetal lung immune cells using scRNA-seq, smFISH, and immunohistochemistry.