Publication

[Scientific Data] Investigators performed a proteomics meta-analysis of public data to refine the plasma extracellular vesicles (EV) composition by separating EV proteins and contaminants into different clusters.

[Scientific Reports] Researchers explored a dual impact of pressure, and volume overload due to aortocaval fistula on Cx43 and extracellular matrix as well as the effect of renin–angiotensin blockade.

[ACS Biomaterials Science & Engineering] Scientists proposed an innovative method based on magneto-mechanical actuation to induce endothelial permeability. This method employed FDA-approved PEGylated superparamagnetic iron oxide nanoparticles and alternating nonheating magnetic fields.

[Journal Of Investigative Dermatology] In a mono-centre exploratory study of 17 adult patients with capillary malformations, scientists found somatic mutations in the GNAQ or GNA11 genes. They applied an endothelial-selective cell isolation protocol to culture primary endothelial cells from skin biopsies from these patients.

[Nature Communications] TAMARIN Phase-II, multicenter, single-arm clinical trial assessed tamoxifen’s safety and activity in patients with stable myeloproliferative neoplasms, no prior thrombotic events and mutated JAK2V617F, CALRins5 or CALRdel52 peripheral blood allele burden ≥20%.

[Haematologica] 301 patients with a median age 60 years were enrolled. Of them, 287 and 274 patients collected ≥2 and ≥4×106 CD34+ cells/kg, respectively, with a median of 9.9×106 CD34+ cells/kg collected.