Tag results:
Publication
Newsletters
Fatty Acid Binding Protein 5 Regulates Docetaxel Sensitivity in Taxane-Resistant Prostate Cancer Cells
[PLOS One] Employing taxane-resistant DU145-TXR cells and a combination of cytotoxicity, apoptosis, and cell cycle assays, scientists' findings demonstrated that fatty acid binding protein 5 knockdown sensitized the cells to docetaxel.
Newsletters
Anti-Proliferative Effect of Cannabidiol in Prostate Cancer Cell PC3 Is Mediated by Apoptotic Cell Death, NFκB Activation, Increased Oxidative Stress, and Lower Reduced Glutathione...
[PLOS One] The authors found that cannabidiol decreased prostate cancer cell viability up to 37.25% and induced apoptotic cell death in a time and dose-dependent manner.
Neural Cell News
Notch1 Cortical Signaling Regulates Epithelial Architecture and Cell–Cell Adhesion
[Journal of Cell Biology] Investigators employed a 3D model of a human ductal epithelium to reveal tissue morphogenic defects result from loss of Notch1, but not Notch1 transcriptional signaling.
Mesenchymal Cell News
An Engineered Periosteum for Efficient Delivery of rhBMP-2 and Mesenchymal Progenitor Cells during Bone Regeneration
[npj Regenerative Medicine] Researchers developed a biocompatible, 3D polycaprolactone melt electro-written membrane to act as a mimetic periosteum.
Mesenchymal Cell News
Regulation of Base Excision Repair During Adipogenesis and Osteogenesis of Bone Marrow-Derived Mesenchymal Stem Cells
[Scientific Reports] The authors investigated how alkyl-damage repair was modulated during adipogenic and osteogenic differentiation, especially focusing on the base excision repair pathway.
Newsletters
Mapping Oto-Pharyngeal Development in a Human Inner Ear Organoid Model
[Development] Using single-cell RNA sequencing at ten stages during the first 36 days of differentiation, researchers tracked the evolution from pluripotency to various ear cell types after exposure to specific signaling modulators.