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Efferocytosis of Viable Versus Heat-Inactivated MSC Induces Human Monocytes to Distinct Immunosuppressive Phenotypes

[Stem Cell Research & Therapy] Researchers sought to dissect MSC’s trophic mechanism from their efferocytic mechanisms and determine if the viability of MSCs prior to efferocytosis influenced the resultant phenotype of monocytes.

Mesenchymal Stromal Cell Secretome Is Affected by Tissue Source and Donor Age

[Stem Cells] Investigators examined the influence of donor age, sex and tissue source, on the protein profile of the equine MSC secretome. They used dynamic metabolic labeling with stable isotopes combined with liquid chromatography-tandem mass spectrometry to identify secreted proteins in MSC conditioned media.

Proliferation-Related Features of the Human Mesenchymal Stem Cells Derived from Palatine Tonsils, Adipose Tissues, and Bone Marrow

[Tissue Engineering And Regenerative Medicine] The authors analyzed the expression levels of 47,000 transcripts in adipose-derived, bone marrow-derived, and tonsil-derived MSCs using GeneChip.

Comprehensive Cell Surface Protein Profiling of Human Mesenchymal Stromal Cells from Peritoneal Dialysis Effluent and Comparison with Those from Human Bone Marrow and Adipose...

[Human Cell] Peritoneal mesenchymal stromal cells were grown in plastic dishes for 4–7 passages, and their cell surface phenotype was examined by staining with a panel of 242 antibodies.

Biocompatibility of Graphene Oxide Nanosheets Functionalized with Various Amino Acids towards Mesenchymal Stem Cells

[Heliyon] Scientists evaluated the cytotoxicity and genotoxicity of graphene oxide synthesized by Hummer's method and functionalized by different amino acids such as lysine, methionine, aspartate, and tyrosine.

MiR-601-Induced BMSCs Senescence Accelerates Steroid-Induced Osteonecrosis of the Femoral Head Progression by Targeting SIRT1

[Cellular and Molecular Life Sciences] The rat steroid-induced osteonecrosis of the femoral head model was constructed, and rat bone marrow mesenchymal stem cells were extracted. Aging-related indicators were detected by SA-β-Gal staining, qRT-PCR, and Western Blot experiments.

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