Review

[Molecular Biology Reports] There is an urgent need for physiological models to study SARS-CoV-2 infection during the pandemic. Human stem cell-derived organoids can provide insight into understanding the SARS-CoV-2 cell entry molecular mechanism.

[Journal Of Controlled Release] Scientists describe the morphological and functional characteristics of tumor blood vessels and summarize the pivotal molecular targets commonly used in nanomedicine design, and then highlight the recent cutting-edge advancements utilizing nanotechnologies for precise regulation of tumor vasculature.

[Biomedicine & Pharmacotherapy] Based on bibliometric studies, the authors first discuss the relationship between oxidative stress-induced endothelial dysfunction and cardiovascular diseases, then summarize the role of melatonin in the treatment of atherosclerosis, hypertension, myocardial ischemia-reperfusion injury, and other cardiovascular diseases.

[Trends In Biotechnology] The authors summarize recent advances in mRNA-based CAR immunotherapies and highlight their opportunities and challenges for the development of a new generation of living drugs.

[Journal Of Clinical Apheresis] Hematopoietic stem cell transplantation is a life-saving procedure that requires mobilization of stem cells for apheresis procedure. The authors aimed to examine mobilizing agents that are in use and under investigation.

[Experimental Hematology] Scientists discuss the central role of the microenvironment in physiologic and pathologic hematopoiesis and the mechanisms of senescence, considered a fundamental protective mechanism against the proliferation of damaged and pre-tumoral cells.