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Review

Engineering Prostate Cancer In Vitro: What Does It Take?

[Oncogene] Scientists highlight the current in vitro 3D prostate cancer (PCa) models with a special focus on organoids and discuss engineering approaches to create more physiologically relevant PCa organoid models.

The Diagnosis and Treatment of Castrate-Sensitive Oligometastatic Prostate Cancer: A Review

[Prostate Cancer and Prostatic Diseases] The authors summarize the definition and classification of oligometastatic prostate cancer, assess the diagnostic methods and imaging modalities utilized, and review the treatment options and outcomes.

The Emerging Family of RORγt+ Antigen-Presenting Cells

[Nature Reviews Immunology] The authors summarize the major findings that led to the discovery of RORγt+ Aantigen-presenting cells and their associated functions, discuss discordance in recent reports, and identify gaps in knowledge in this burgeoning field.

Decoding Hepatocarcinogenesis from a Noncoding RNAs Perspective

[Journal Of Cellular Physiology] Scientists shed light on future trends, thereby discussing the pathological roles of lncRNAs and circRNAs in HCC proliferation, migration, and epithelial-to-mesenchymal transition.

Cellular Heterogeneity and Plasticity during NAFLD Progression

[Frontiers in Molecular Biosciences] Investigators provided insights into non-alcoholic fatty liver disease (NAFLD) heterogeneity by addressing cellular plasticity and metabolic adaptation of hepatocytes, hepatic stellate cells, and Kupffer cells during NAFLD progression.

Tibolone and Breast Tissue: A Review

[Reproductive Sciences] The authors provide an updated narrative review focusing on the impact of tibolone on breast. They report data from major preclinical and clinical studies regarding the effects of the use of this compound on breast tissue and breast density.

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