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Liver Sinusoidal Endothelial Cell: An Important Yet Often Overlooked Player in the Liver Fibrosis

The authors update the various pathways by which liver sinusoidal endothelial cells are involved in the initiation and progression of liver fibrosis, including but not limited to cellular phenotypic change, the...

Endocrinology of the Aging Prostate: Current Concepts

[Frontiers In Endocrinology] Scientists systematically review the impact of hormonal changes that occur during aging on the prostate, including the role of sex hormones, insulin-like growth factor 1, thyroid hormones, and insulin.

Intestinal Stem Cells: Guardians of Homeostasis in Health and Aging amid Environmental Challenges

[Experimental & Molecular Medicine] The authors explore the regulatory mechanisms that govern intestinal stem cell behavior, emphasizing the dynamic adaptability of the intestinal epithelium in the face of various challenges.

Mineralocorticoid Receptors in Vascular Smooth Muscle: Blood Pressure and Beyond

[Hypertension] The authors summarize the latest understanding of the molecular mechanisms by which smooth muscle cell-mineralocorticoid receptor contributes to regulation of vasomotor function and blood pressure , and more.

Dormancy of Cutaneous Melanoma

[Cancer Cell International] The authors focus on the mechanisms regulating the initiation of cutaneous melanoma dormancy as well as those that are involved in the reawakening of dormant cutaneous melanoma cells.

Regulatory T Cell: A Double-Edged Sword From Metabolic-Dysfunction-Associated Steatohepatitis to Hepatocellular Carcinoma

[eBioMedicine] Recent studies have unveiled distinct behaviors of Tregs at different stages of metabolic-dysfunction-associated steatotic liver disease (MASLD), suggesting a dual role in the pathogenesis. The authors explore the fate of Tregs from MASLD to HCC, offering recent insights into potential targets for clinical intervention.

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