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Review

Stem Cell Transplantation for Systemic Sclerosis

[Cochrane Database of Systematic Reviews] Scientists assess the benefits and harms of autologous hematopoietic stem cell transplantation for the treatment of systemic sclerosis.

Understanding COVID-19-Associated Coagulopathy

[Nature Reviews Immunology] Investigators categorize the current understanding of COVID-19-associated coagulopathy into three main pathological mechanisms: first, vascular endothelial cell dysfunction; second, a hyper-inflammatory immune response; and last, hypercoagulability.

P2Y1R and P2Y2R: Potential Molecular Triggers in Muscle Regeneration

[Purinergic Signalling] The authors summarize muscle regeneration via P2Y1R and P2Y2R and speculated that P2Y1R and P2Y2R might be potential molecular triggers for muscle stem cells’ activation and proliferation via the p-ERK1/2 and PLC pathways.

Transcriptional Regulation of Vascular Smooth Muscle Cell Proliferation, Differentiation and Senescence: Novel Targets for Therapy

[Vascular Pharmacology] The authors reviewed recent advances in their understanding of regulatory mechanisms governing smooth muscle cell phenotypic modulation.

Regulatory T Cells in Skeletal Muscle Repair and Regeneration: Recent Insights

[Cell Death & Disease] Tregsregulate homeostasis within the immune system and self-immune tolerance, and play a crucial role in skeletal muscle repair and regeneration.

A Conserved Bacteroidetes Antigen Induces Anti-Inflammatory Intestinal T Lymphocytes

[Cell Death & Disease] Tregsregulate homeostasis within the immune system and self-immune tolerance, and play a crucial role in skeletal muscle repair and regeneration.

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