Review

[Stem Cells And Development] The purpose of this narrative review is to identify barriers to canine SCR on molecular and cellular levels, using comparative research to inform potential solutions to their use in both research and clinical contexts.

[Molecular Psychiatry] The authors focus on the association between the brain-based paravascular drainage pathway known as the “glymphatic system” and traumatic brain injury-related neurodegeneration.

[Signal Transduction And Targeted Therapy] The authors present the strengths and weaknesses of patient-derived xenograft models and highlight the integration of novel technologies in patient-derived xenograft model research.

[Nature Cancer] Scientists discuss insights into the tumor-modulating roles of autophagy in different contexts and reflect on how future studies using physiological culture systems may help to understand the complexity and open new therapeutic avenues.

[Bone Marrow Transplantation] The authors update knowledge regarding the diagnosis and severity assessment of sinusoidal obstruction syndrome, also known as veno-occlusive disease in adult patients, and also its pathophysiology and treatment.

[Cellular & Molecular Immunology] Scientists summarize the current knowledge on the immunomodulatory and therapeutic properties of MSCs with a focus on MSC apoptosis as a key mechanism to elicit immunosuppression.