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Tissue-Specific Macrophages: How They Develop and Choreograph Tissue Biology

[Nature Reviews Immunology] Scientists summarize our growing knowledge of macrophage diversity, how macrophage subsets orchestrate tissue development and function, and further interrelate macrophage ontogeny with their core functions across tissues — that is, the signaling events within the macrophage niche that may control organ functionality during development, homeostasis and aging.

Understanding COVID-19 in Children: Immune Determinants and Post-Infection Conditions

[Pediatric Research] The authors analyzed the main results of the recent literature assessing immune response to SARS-CoV-2 over the pediatric age group, summarizing such observations by dividing them into innate and acquired immunity, then reporting how altered immune responses can determine post-infectious conditions.

Genome-Engineering Technologies for Modeling and Treatment of Cystic Fibrosis

[Advances In Medical Sciences] The authors outline the potential and possibilities of using CRISPR/Cas9-based gene-editing technology in cystic fibrosis modeling.

Biomaterial-Based Platforms for Modulating Immune Components against Cancer and Cancer Stem Cells

[Acta Biomaterialia] Scientists describe the cutting-edge research undertaken in the field of nanotechnology and material science to develop biomaterials-based platforms as effective immunotherapeutics.

The Molecular Pathology of Schizophrenia: An Overview of Existing Knowledge and New Directions for Future Research

[Molecular Psychiatry] The authors overview the current knowledge acquired from these studies, their limitations, and directions for future research that may redefine schizophrenia based on biological alterations in the responsible organ rather than operationalized criteria.

Immune Determinants of the Pre-Metastatic Niche

[Cancer Cell] The authors discuss recent advances in our understanding of the tumor immune microenvironment and provide a comprehensive overview of the immune determinants of the pre-metastatic niches' spatiotemporal evolution.

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