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Vaccines as Treatments for Prostate Cancer

[Nature Reviews Urology] The authors describe the history of vaccines as treatments for prostate cancer and discuss vaccines that have been assessed in phase III clinical trials, as well as other vaccines and combination approaches that have been tested or are currently being evaluated in clinical trials.

Prospective Role of 3βHSD1 in Prostate Cancer Precision Medicine

[The Prostate] Investigators review the recent advance on 3β-hydroxysteroid dehydrogenase 1 (3βHSD1) inhibitors and targeting 3βHSD1 for prostate cancer management.

Cell Therapy for Parkinson’s Disease with Induced Pluripotent Stem Cells

[Inflammation and Regeneration] In the context of immune rejection, there are several modes of stem cell-based therapies. The authors discuss several practical points of stem cell-based therapies for Parkinson's disease.

Induced Pluripotent Stem Cells in the Era of Precise Genome Editing

[Current Stem Cell Research & Therapy] Investigators cover the remarkable progress that has been made in the use of genome editing tools in iPSCs, their applications in disease research and gene therapy, as well as the hurdles that remain in the actual implementation of CRISPR/Cas systems.

Advances in Understanding the Role and Mechanisms of Tumor Stem Cells in HER2-Positive Breast Cancer Treatment Resistance

[International Journal of Oncology] The authors review the roles of breast CSCs in the occurrence, development, and management of breast cancer treatment resistance.

Relevance of Glyco-Biomakers and Glycan Profiles in Cancer Stem Cells

[Glycobiology] Investigators discuss the function of carbohydrates as prospective serum biomarkers, some clinically authorized biomarkers, and potential novel biomarkers relating to cancer disease diagnosis and prognosis.

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