Tag results:


The Metabolic Nature of Inflammatory Bowel Diseases

[Nature Reviews Gastroenterology & Hepatology] The authors review experimental and clinical evidence for the metabolic nature of gut inflammation in IBD and delineate distinct parallels to the inflammatory state in metabolic diseases.

Three-Dimensional (3D) Cell Culture: A Valuable Step in Advancing Treatments for Human Hepatocellular Carcinoma

[Cancer Cell International] The authors shed light on various established 3D culture models of HCC and their role in the investigation of tumour-tumor microenvironment interactions and HCC-related therapeutic resistance.

Recent Advances in the Therapeutic Efficacy of Hepatocyte Growth Factor Gene-Modified Mesenchymal Stem Cells in Multiple Disease Settings

[Journal of Cellular and Molecular Medicine] Scientists focus on studies involving hepatocyte growth factor (HGF)/mesenchymal stem cells (MSCs) both in vitro and in vivo. The characteristics of HGF/MSCs are summarized, and the mechanisms of their improved therapeutic efficacy are analyzed.

Mitochondria, Mitophagy, and the Role of Deubiquitinases as Novel Therapeutic Targets in Liver Pathology

[Journal of Cellular Biochemistry] Investigators focus on the role of different deubiquitinases on mitophagy and their contribution to nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, alcohol-related liver disease, and especially HCC.

The Role of the Gut Microbiota in Multiple Sclerosis

[Nature Reviews Neurology] Scientists examine the influence that the gut microbiota have on immune function via modulation of serotonin production in the gut and through complex interactions with components of the immune system, such as T cells and B cells.

Exosomes Rewire the Cartilage Microenvironment in Osteoarthritis: From Intercellular Communication to Therapeutic Strategies

[International Journal of Oral Science] The authors summarize the current insight regarding the biogenesis and function of exosomes and their potential as therapeutic tools targeting cell-to-cell communication in osteoarthritis (OA), suggesting new realms to improve OA management.