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Review

Chimeric Antigen Receptor-Based Natural Killer Cell Immunotherapy in Cancer: From Bench to Bedside

[Cell Death & Disease] The authors provide an updated understanding of NK cell development, functions, and their applications in disease therapy. They explored the rationale for utilizing engineered NK cell therapies, such as CAR-NK cells, and discuss the differences between CAR-T and CAR-NK cells.

Future of Low Back Pain: Unravelling Ivd Components and MSCs’ Potential

[Cell Regeneration] The authors conduct a comprehensive research to further understand the intertwine between the mechanisms of action of intervertebral disc (IVD) components and the therapeutic potential of MSCs, exploring their characteristics, and how to optimize their use and establish them safely in distinct settings for low back pain treatment.

Role of Long Noncoding RNA in Regulating HIV Infection-A Comprehensive Review

[mBio] The authors provide an overview of the current knowledge regarding how lncRNAs regulate HIV gene expression, categorizing them as either activators or inhibitors of viral gene expression and infectivity.

Silent Battles: Immune Responses in Asymptomatic SARS-CoV-2 Infection

[Cellular & Molecular Immunology] Scientists focused on asymptomatic infections, a widely reported phenomenon that has substantially contributed to the rapid spread of the pandemic.

Bioengineering and Vascularization Strategies for Islet Organoids: Advancing Toward Diabetes Therapy

[Metabolism Clinical And Experimental] The authors summarize the latest developments in bioengineering functional islet organoids in vitro and promoting vascularization of organoid grafts before and after transplantation.

The NF-κB Signaling System in the Immunopathogenesis of Inflammatory Bowel Disease

[Science Signaling] Investigators summarize their knowledge of the roles of these NF-κB pathways, which are activated in different intestinal cell types by specific ligands, and their cross-talk, in fueling aberrant intestinal inflammation.

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