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The Strategies to Cure Cancer Patients by Eradicating Cancer Stem-Like Cells

[Molecular Cancer] Increasing evidence indicated that specific biomarkers, aberrant activated pathways, immunosuppressive tumor microenvironment (TME), and immunoevasion are considered the culprits in the occurrence of CSCs and the maintenance of CSCs properties including multi-directional differentiation.

Engineered Extracellular Vesicles: A Potential Treatment for Regeneration

[iScience] The authors comprehensively analyze the engineering methods utilized for modifying donor cells and extracellular vesicles, with a focus on comparing the therapeutic potential between engineered and natural extracellular vesicles.

Nutraceuticals and Biotics in Pediatric Gastrointestinal Disorders

[European Journal Of Clinical Nutrition] The authors provide clinicians with guidance on the use of complementary therapies for pediatric gastrointestinal symptoms and disorders, highlighting the scarcity of studies on the kinetics and dynamics of nutraceuticals and biotics.

Endothelium-Derived Dopamine and 6-Nitrodopamine in the Cardiovascular System

[Physiology] The authors propose that endothelium-derived catecholamines may constitute a major mechanism for control of vascular tone and heart functions, in contrast to the overrated role attributed to the autonomic nervous system.

Dental Pulp Stem Cells for Bone Tissue Engineering: A Literature Review

[Stem Cells International] The authors review the biological characteristics of dental pulp stem cells, their potential for bone tissue engineering, and the underlying transcription factors and signaling pathways involved in osteogenic differentiation.

Regulation and Signaling Pathways in Cancer Stem Cells: Implications for Targeted Therapy for Cancer

[Molecular Cancer] The maintenance of CSC characteristics plays a pivotal role in driving CSC-associated tumor metastasis and conferring resistance to therapy. Consequently, CSCs have emerged as promising targets in cancer treatment.

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