Review

[Archives Of Toxicology] Scientists summarize the hallmark features of ferroptosis and then analyze the exact mechanisms by which ferroptosis is precisely regulated at multiple levels and links.

[Cell Stem Cell] The authors describe central features of HSC regulation during ontogeny to contextualize how adaptive responses over the life of the organism ultimately form the basis for HSC functional degradation with age.

[Science Translational Medicine] The authors highlight the intricate interactions between astrocytes, other CNS-resident cells, and CNS-infiltrating cells as well as their potential therapeutic value in the context of inflammation and neurodegeneration.

[ACS Materials Au] The authors provide an overview of the design, preparation, methodology, and oncological aspects of organic polymeric nanoparticles-based photodynamic therapy for the treatment of prostate cancer.

[Journal Of Hepatology] One of the most striking features of PSC is its association with inflammatory bowel disease (IBD), with the majority of patients with PSC being diagnosed with extensive colitis. The authors describesthe epidemiology of IBD in PSC, its specific phenotype, complications and potential pathophysiological mechanisms connecting the two diseases.

[Molecular Neurodegeneration] Scientists cover the current understanding of the molecular mechanisms of cyclic GMP-AMP synthase (cGAS) activation and highlight cGAS-stimulator of interferon genes (STING) signaling in various cell types of central and peripheral nervous systems, such as resident brain immune cells, neurons, and glial cells.