Publication

[Stem Cell Research] The authors reprogrammed pEP4EO2SEN2K and pEP4EO2SET2K, pCEP4-M2L was electrotransfected in T2DM patients with pEP4EO2SEN2K, and pCEP4-M2L was electrotransfected in T2DM patients expressing the OCT4, SOX2, NANOG, LIN28, c-MYC, KLF4, and SV40LT transcription factors to obtain induced pluripotent stem cells

[ACS Nano] The authors reported a superelastic cellular-structured bioactive glass nanofibrous cryogel (BGNC) composed of highly flexible BG nanofibers and citric acid-cross-linked poly(vinyl alcohol).

[Proceedings Of The National Academy Of Sciences Of The United States Of America] Investigators applied a single-cell barcode-based lineage tracing method, called CellTagging, to track the fate of SCGB3A2/SFTPB/CFTR cells during airway organoid differentiation in vitro.

[JCI Insight] To test if β1-containing integrins are required during repair following acute injury, scientists administered E. coli lipopolysaccharide (LPS) by intratracheal injection to mice with a post-developmental deletion of β1 integrin in AT2 cells. β1-deficient AT2 cells showed persistently increased proliferation after injury, which was blocked by inhibiting NF-kB activation.

[Microbiology Spectrum] Scientists compared phenotypes and proinflammatory properties of A. xylosoxidans, A. dolens, A. insuavis, and A. ruhlandii using in vitro models. Bacterial supernatants were used to stimulate cystic firbosis bronchial epithelial cells and whole blood from healthy individuals.

[Phytotherapy Research] Investigators studied the effect of magnolol on alleviating fibrosis in COPD based on transient receptor potential vanilloid 4 (TRPV4), and to further analyze its mechanism of action on TRPV4.