Publication

[Journal Of Controlled Release] Scientists constructed a bio-responsive Au-miR-183 inhibitor delivery system targeting liver cancer stem cells, and adopted the strategy of combining αPD-L1 immunotherapy.

[Discover Oncology] Consensus clustering analysis was performed to subtype HCC patients in The Cancer Genome Atlas database. Differentially expressed genes among the subtypes were filtered and subjected to the least absolute shrinkage and selection operator regression analysis and univariate Cox regression analysis to filter prognostic genes.

[Advanced Materials] Scientists presented a novel cochlear organoids integrated conductive hydrogel biohybrid system with cochlear implant electroacoustic stimulation for cochlea-on-a-chip construction and high-throughput drug screening.

[Advanced Drug Delivery Reviews] Researchers described engineering strategies and alternative biocompatible materials that could facilitate the practical applications of organoids in regenerative medicine.

[Nature Communications] Researchers showed that the efficacy of cancer immunotherapies was compromised by the accumulation of senescent cells in mice and in the context of therapy-induced senescence

[Scientific Reports] Investigators demonstrated that β-escin and Aesculus hippocastanum L. have antiviral and virucidal activities against SARS-CoV-2 and CCoV, revealing broad-spectrum antiviral activity against coronaviruses.