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High TXNIP Expression Accelerates the Migration and Invasion of the GDM Placenta Trophoblast

[BMC Pregnancy and Childbirth] The expression and localization of thioredoxin-interacting protein (TXNIP) in the placenta of gestational diabetes mellitus (GDM) patients and the health control was investigated.

Activation of Atg5-Dependent Placental Lipophagy Ameliorates Cadmium-Induced Fetal Growth Restriction

[Environmental Pollution] Researchers explored the role of placental lipophagy in cadmium-induced fetal growth restriction utilizing case-control study, animal experiments, and cultures of primary human placental trophoblast.

High Dimensional Analysis Reveals Distinct NK Cell Subsets but Conserved Response to Stimulation in Umbilical Cord Blood and Adult Peripheral Blood

[European Journal of Immunology] Investigators showed that umbilical cord blood natural killer cells express slightly higher levels of the immune checkpoints PD-1, TIGIT and CD96 compared to their adult peripheral blood counterparts.

Lung-Specific McEmp1 Functions as an Adaptor for KIT to Promote SCF-Mediated Mast Cell Proliferation

[Nature Communications] The authors reported that mast cell-expressed membrane protein1 (MCEMP1), a lung-specific surface protein, functions as an adaptor for KIT, which promotes stem cell factor (SCF)-mediated mast cell proliferation.

IRAK-M Has Effects in Regulation of Lung Epithelial Inflammation

[Respiratory Research] IL-1 receptor-associated kinase (IRAK)-M expression was significantly induced in BEAS-2B and A549 cells after inflammatory stimulation.

SARS-CoV-2 Infection Aggravates Cigarette Smoke-Exposed Cell Damage in Primary Human Airway Epithelia

[Virology Journal] Investigators evaluated the role of cigarette smoke on SARS-CoV-2-induced immune and inflammatory responses, and epithelial barrier integrity leading to airway epithelial damage.

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