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Host Brain Environmental Influences on Transplanted Medial Ganglionic Eminence Progenitors

[Scientific Reports] Investigators systematically evaluated the influence of age and brain region on survival, migration, and differentiation of transplant-derived cells.

Endometrial Mesenchymal Stromal/Stem Cells Improve Regeneration of Injured Endometrium in Mice

[Biological Research] Electrocoagulation was applied to the left uterine horn of NOD/SCID mice causing endometrial injury. Human endometrial MSCs or phosphate-buffered saline was then injected into the left injured horn while the right normal horn served as controls.

Neoteric Semiembedded β-Tricalcium Phosphate Promotes Osteogenic Differentiation of Mesenchymal Stem Cells under Cyclic Stretch

[ACS Applied Materials & Interfaces] A novel semiembedded technique was utilized to anchor β-TCP nanoparticles onto the surface of the elastic polymer, followed by hydrophilic modification with the polymerization of dopamine.

Mesenchymal Stem Cell-Derived Extracellular Vesicles Exert Pro-Angiogenic and Pro-Lymphangiogenic Effects in Ischemic Tissues by Transferring Various microRNAs and Proteins Including ITGa5 and NRP1

[Journal Of Nanobiotechnology] Investigators analyzed biological effects of bone marrow MSC-extracellular vesicles on endothelial cells in ischemic tissues both in in vitro and in vivo conditions and elucidated the molecular mechanisms underlying the tissue repair.

Icariin Promotes Bone Marrow Mesenchymal Stem Cells Osteogenic Differentiation via the mTOR/Autophagy Pathway to Improve Ketogenic Diet-Associated Osteoporosis

[Journal Of Orthopaedic Surgery And Research] Thirty mice were divided into: sham, ketogenic diet (KD), and KD + icariin groups. Post a 12-week intervention, evaluation including bone microstructures, serum concentrations of tartrate-resistant acid phosphatase and bone-specific alkaline phosphatase, and femoral tissue expression levels of osteocalcin and TRAP.

Suppression of MALAT1 Promotes Human Synovial Mesenchymal Stem Cells Enhance Chondrogenic Differentiation and Prevent Osteoarthritis of the Knee in a Rat Model via Regulating...

[Cell And Tissue Research] To determine whether or not hSMSC might differentiate, researchers used a number of different culture settings and labeling techniques.

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