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m6A Demethylase ALKBH5 Maintains Stemness of Intrahepatic Cholangiocarcinoma by Sustaining BUB1B Expression and Cell Proliferation

[Translational Oncology] Bioinformatic analyses of The Cancer Genome Atlas data were performed, and the association of alkB homolog 5 (ALKBH5) in predicting overall survival in patients with intrahepatic cholangiocarcinoma was investigated.

c-MET-Positive Circulating Tumor Cells and Cell-Free DNA as Independent Prognostic Factors in Hormone Receptor-Positive/HER2-Negative Metastatic Breast Cancer

[Breast Cancer Research] Ninety-seven patients with hormone receptor-positive metastatic breast cancer were prospectively enrolled during standard treatment at Samsung Medical Center.

Establishment of Tumor Microenvironment-Preserving Organoid Model from Patients with Intracranial Meningioma

[Cancer Cell International] The biological features of meningioma organoids (MNOs) were evaluated using WST, LDH, and collagen-based 3D invasion assays.Cellular identities in MNOs were confirmed by immunohistochemistry.

Hindbrain Boundaries as Niches of Neural Progenitor/Stem Cells Regulated by the Extracellular Matrix Proteoglycan Chondroitin Sulphate

[Development] To address whether chondroitin sulphate proteoglycan was significant for hindbrain development, its expression was manipulated in vivo and in vitro.

The Role of PLAG1 in Mouse Brain Development and Neurogenesis

[Molecular Neurobiology] Investigators reported the spatial distribution and functional implications of pleomorphic adenoma gene 1 (PLAG1) expression in the adult mouse brain.

Bioinformatic Analysis Reveals an Association between Metadherin with Breast Cancer Prognosis and Tumor Immune Infiltration

[Scientific Reports] Investigators found that Metadherin was overexpressed in breast cancer and was significantly correlated with individual cancer stage, age, subclasses, menopause and nodal metastasis status.

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