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Cancer Stem Cell News
m6A Demethylase ALKBH5 Maintains Stemness of Intrahepatic Cholangiocarcinoma by Sustaining BUB1B Expression and Cell Proliferation
[Translational Oncology] Bioinformatic analyses of The Cancer Genome Atlas data were performed, and the association of alkB homolog 5 (ALKBH5) in predicting overall survival in patients with intrahepatic cholangiocarcinoma was investigated.
Cancer Stem Cell News
c-MET-Positive Circulating Tumor Cells and Cell-Free DNA as Independent Prognostic Factors in Hormone Receptor-Positive/HER2-Negative Metastatic Breast Cancer
[Breast Cancer Research] Ninety-seven patients with hormone receptor-positive metastatic breast cancer were prospectively enrolled during standard treatment at Samsung Medical Center.
Newsletters
Establishment of Tumor Microenvironment-Preserving Organoid Model from Patients with Intracranial Meningioma
[Cancer Cell International] The biological features of meningioma organoids (MNOs) were evaluated using WST, LDH, and collagen-based 3D invasion assays.Cellular identities in MNOs were confirmed by immunohistochemistry.
Neural Cell News
Hindbrain Boundaries as Niches of Neural Progenitor/Stem Cells Regulated by the Extracellular Matrix Proteoglycan Chondroitin Sulphate
[Development] To address whether chondroitin sulphate proteoglycan was significant for hindbrain development, its expression was manipulated in vivo and in vitro.
Neural Cell News
The Role of PLAG1 in Mouse Brain Development and Neurogenesis
[Molecular Neurobiology] Investigators reported the spatial distribution and functional implications of pleomorphic adenoma gene 1 (PLAG1) expression in the adult mouse brain.
Mammary Cell News
Bioinformatic Analysis Reveals an Association between Metadherin with Breast Cancer Prognosis and Tumor Immune Infiltration
[Scientific Reports] Investigators found that Metadherin was overexpressed in breast cancer and was significantly correlated with individual cancer stage, age, subclasses, menopause and nodal metastasis status.