Publication

[Osteoarthritis And Cartilage] Chondrocytes were isolated from juvenile bovine knee joints and cultured with (primed) or without (unprimed) a growth factor cocktail. Gene expression, cell morphology, cell adhesion, cytoskeletal protein distribution, and cell mechanics were assessed.

[International Journal Of Biological Macromolecules] Investigators highlight recent advances in the development of biopolymers from agro-food waste and their potential for future tissue engineering and regenerative medicine applications, including drug delivery, wound healing, tissue engineering, and more.

[Advanced Materials] Researchers designed a protease-activated fibronectin (FN1) and/or tenascin C (TNC) binding peptide (FTF) and propose an ECM-trapped bioinspired lipoprotein that could be preferentially captured by the TNC and/or FN1 for tumor retention, and then be responsively dissociated from the matrix to potentiate the antitumor immunity.

[Science Advances] Investigators identified cell clusters representing various neuron types, glia, endothelial cells, pericytes, fibroblasts, and T cells and investigated cell type–dependent alterations in gene expression in Parkinson's disease.

[Biotechnology And Bioengineering] Investigators developed a highly efficient method for generating functional liver organoids from hiPSC-derived carboxypeptidase M liver progenitor cells, using a microwell structure, and enhanced maturation through direct oxygenation in oxygen-permeable culture plates.

[Scientific Reports] To gain more accurate understanding, the effects of T-2 toxin were investigated in the present study in chicken-derived 3D primary hepatic cell cultures. 3D spheroids were treated with three concentrations of T-2 toxin for 24 hours.