Tag results:

Publication

Coordinated Activation of DNMT3a and TET2 in Cancer Stem Cell-Like Cells Initiates and Sustains Drug Resistance in Hepatocellular Carcinoma

[Cancer Cell International] Scientists addressed whether and how dysregulated epigenetic regulators have regulatory and functional communications in establishing and maintaining drug resistance.

89Zr-Labeled ImmunoPET Targeting the Cancer Stem Cell Antigen CD133 Using Fully-Human Antibody Constructs

[EJNMMI Research] Zirconium-89-radiolabeled immunoPET probes that target the cancer stem cell-antigen CD133 were developed using fully human antibody and antibody scFv-Fc scaffolds.

Exercise Affects High-Fat Diet-Stimulated Breast Cancer Metastasis through Irisin Secretion by Altering Cancer Stem Cell Properties

[Biochemistry And Biophysics Reports] Experimental metastasis was induced after eight weeks of steady exercise using a mouse model. Furthermore, one of the myokines, irisin, was studied to elucidate the effects of metastasis-regulating protein expression, and colony and sphere formation, which are cancer stem cell properties.

TMEM120B Strengthens Breast Cancer Cell Stemness and Accelerates Chemotherapy Resistance via β1-Integrin/FAK-TAZ-mTOR Signaling Axis by Binding to MYH9

[Breast Cancer Research] Investigators determined the role of TMEM120B in transcriptional coactivator with PDZ-binding motif-mediated CSC expansion and chemotherapy resistance.

ADAR2 Deficiency Ameliorates Non-Alcoholic Fatty Liver Disease and Muscle Atrophy through Modulating Serum Amyloid A1

[Journal Of Cachexia Sarcopenia And Muscle] ADAR2+/+/GluR-BR/R mice and ADAR2−/−/GluR-BR/R mice were subjected to feeding with standard chow or high-fat diet for 20 weeks at the age of 5 weeks.

CircHAS2 Activates CCNE2 to Promote Cell Proliferation and Sensitizes the Response of Colorectal Cancer to Anlotinib

[Molecular Cancer] Investigators sought to determine the potential functions and specific mechanisms of circHAS2 in colorectal cancer progression and its role in predicting clinical response to anlotinib. CircHAS2 was a potent biomarker predictive of anlotinib sensitivity, both in patient-derived organoids and xenograft models.

Popular