Publication

[Molecular Biology Reports] Chaperonin containing TCP1 subunit 2 (CCT2) expression and prognostic value in epithelial ovarian cancer samples were assessed according to TCGA dataset. CSC traits were evaluated by RT-PCR, WB assays, sphere-forming assays and chemoresistance analysis.

[NPJ Vaccines] Shigella virulence factor VirG was highly conserved among Shigella strains and appealing as a broad-spectrum vaccine candidate. They investigated the immunogenicity and protective capacity of VirG as a subunit vaccine in mice.

[Nature Communications] Scientists identified Mcam, a potential member of the non-canonical Wnt signaling, as an important negative regulator of mammary gland epithelial cells by genome-scale CRISPR-Cas9 knockout library screening.

[Journal Of Investigative Dermatology] Researchers reported a strong downregulation of epithelial Wnt/β-catenin activity as the mammary bud progressed to branching.

[Stem Cells And Development] Researchers compared extracellular vesicles isolated from two tissue sources of MSCs that were exposed to various cell culture conditions and evaluated their anti-inflammatory effects. Bone marrow and umbilical cord-derived MSCs were exposed to either a serum-free media environment, an inflammatory environment or media supplemented with 5% EV depleted fetal bovine serum.

[Applied Biochemistry And Biotechnology] Since the connection between cells and matrix was provided by transmembrane integrin receptors, scientists aimed at studying the dynamics of signaling pathways associated with integrins on an in vitro model of wound healing using human skin fibroblasts.