Publication

[Scientific Reports] The authors explored the expression profiles of chemokines and chemokine receptors and constructed a chemokine- and chemokine receptor-based signature in female patients with advanced colorectal adenocarcinoma.

[Biomolecules & Therapeutics] Investigators explored the effects of bortezomib (BTZ) on rat neural stem cells. BTZ induced cell death, but the percentage of neurons was increased in the presence of mitogens.

[Neurochemical Research] NSCs were induced by oxygen-glucose deprivation/reoxygenation for constructing cerebral ischemic stroke cell model.

[Nature Biomedical Engineering] The authors reported an lipid nanoparticle-screening method for the optimization of the type of helper lipid and of lipid-component ratios to enhance the delivery of tumor-antigen-encoding mRNA to dendritic cells and their immune-activation profile towards enhanced antitumor activity.

[Journal of Cell Biology] Scientists showed that B lymphoid tyrosine kinase (BLK) positively regulated TLR/IL-1R–mediated inflammatory response. BLK-deficient mice produced less inflammatory cytokines and were more resistant to death upon IL-1β challenge.

[Cancer Immunology Research] Using a mouse model of ovarian cancer, researchers demonstrated the oncolytic effect and immune-modulatory capacities of CARG-2020.