Publication

[Toxicology In Vitro] Researchers generated three-dimensional multi-cell-type liver organoids from HepaRG cells, primary human macrophages, and hepatic-stellate-cell-derived LX-2 cells.

[Hepatology] Investigators presented a novel, multicellular liver organoid model using a co-culture system of macrophages and liver organoids differentiated from the same human pluripotent stem cells.

[Biomaterials Advances] Researchers proposed a tissue engineering strategy using uterine endometrium-derived mesenchymal stem/stromal cells (eMSC) delivered with degradable poly L-lactic acid-co-poly ε-caprolactone (PLACL) and evaluated the immunomodulatory mechanism at the material interfaces.

[ACS Nano] Inspired by the components and functions of the meniscus, scientists developed a self-lubricating and friction-responsive hydrogel that contains nanoliposomes loaded with diclofenac sodium and Kartogenin for anti-inflammation and cartilage regeneration.

[ACS Nano] Scientists modified mRNA-lipid nanoparticles with the fusogenic coiled-coil peptides and demonstrated efficient mRNA delivery to difficult-to-transfect induced pluripotent stem-cell-derived cardiomyocytes.

[Nature Communications] The authors developed CAR T cells against multiple myeloma using a binder to targeting transmembrane activator and CAML interactor in mono and dual-specific formats with anti-B cell maturation antigen (BCMA).