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Safety and Immunogenicity of the Third and Fourth Doses of Vaccine Against SARS-CoV-2 Following a 2-Dose Regimen of Inactivated Whole-Virion SARS-CoV-2 Vaccine

[Scientific Reports] Investigators determined the seroconversion rate of neutralizing antibodies against wild-type SARS-CoV-2 and VOCs at day 28 after the third dose of vaccine and day 28 after the fourth dose of vaccine.

Heat Shock Protein 27 in the Pathogenesis of COVID-19 and Non-COVID Acute Respiratory Distress Syndrome

[Cell Stress & Chaperones] Researchers implicated heat shock protein 27 as a marker of advanced pathogenesis of disease contributing to the dysregulated systemic inflammation and worse clinical outcomes in COVID-19 acute respiratory distress syndrome and therefore may represent a potential therapeutic target.

Kisspeptin-10 Increases Collagen Content in the Myocardium by Focal Adhesion Kinase Activity

[Scientific Reports] Researchers indicated that kisspeptin-10 (KiSS-10) significantly increased the content of intracellular collagen in the myocardium. The inhibition of focal adhesion kinase negated the stimulatory effect of KiSS-10 on collagen deposition in vitro.

CD201+ Fascia Progenitors Choreograph Injury Repair

[Nature] Researchers identified a multipotent fibroblast progenitor marked by CD201 expression in the fascia, the deepest connective tissue layer of the skin.

Effects of Green Light-Emitting Diode Irradiation on Hepatic Differentiation of Hepatocyte-Like Cells Generated from Human Adipose-Derived Mesenchymal Cells

[Scientific Reports] Scientists investigated the effect of green LED irradiation on the differentiation of adipocyte-derived mesenchymal cells into hepatocyte-like cells and the mechanism of its action.

BRISC Is Required for Optimal Activation of NF-κB in Kupffer Cells Induced by LPS and Contributes to Acute Liver Injury

[Cell Death & Disease] Researchers investigated the pathophysiological role of BRCC3 isopeptidase complex (BRISC) in acute liver failure using a mice model induced by D-galactosamine plus lipopolysaccharide.

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