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Immunology of Infectious Disease News
Safety and Immunogenicity of the Third and Fourth Doses of Vaccine Against SARS-CoV-2 Following a 2-Dose Regimen of Inactivated Whole-Virion SARS-CoV-2 Vaccine
[Scientific Reports] Investigators determined the seroconversion rate of neutralizing antibodies against wild-type SARS-CoV-2 and VOCs at day 28 after the third dose of vaccine and day 28 after the fourth dose of vaccine.
Immunology of Infectious Disease News
Heat Shock Protein 27 in the Pathogenesis of COVID-19 and Non-COVID Acute Respiratory Distress Syndrome
[Cell Stress & Chaperones] Researchers implicated heat shock protein 27 as a marker of advanced pathogenesis of disease contributing to the dysregulated systemic inflammation and worse clinical outcomes in COVID-19 acute respiratory distress syndrome and therefore may represent a potential therapeutic target.
Extracellular Matrix News
Kisspeptin-10 Increases Collagen Content in the Myocardium by Focal Adhesion Kinase Activity
[Scientific Reports] Researchers indicated that kisspeptin-10 (KiSS-10) significantly increased the content of intracellular collagen in the myocardium. The inhibition of focal adhesion kinase negated the stimulatory effect of KiSS-10 on collagen deposition in vitro.
Extracellular Matrix News
CD201+ Fascia Progenitors Choreograph Injury Repair
[Nature] Researchers identified a multipotent fibroblast progenitor marked by CD201 expression in the fascia, the deepest connective tissue layer of the skin.
Hepatic Cell News
Effects of Green Light-Emitting Diode Irradiation on Hepatic Differentiation of Hepatocyte-Like Cells Generated from Human Adipose-Derived Mesenchymal Cells
[Scientific Reports] Scientists investigated the effect of green LED irradiation on the differentiation of adipocyte-derived mesenchymal cells into hepatocyte-like cells and the mechanism of its action.
Hepatic Cell News
BRISC Is Required for Optimal Activation of NF-κB in Kupffer Cells Induced by LPS and Contributes to Acute Liver Injury
[Cell Death & Disease] Researchers investigated the pathophysiological role of BRCC3 isopeptidase complex (BRISC) in acute liver failure using a mice model induced by D-galactosamine plus lipopolysaccharide.