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Enniatin A Inhibits the Chaperone Hsp90 and Unleashes the Immune System Against Triple-Negative Breast Cancer

[iScience] The authors discovered that the natural product Enniatin A targeted Hsp90 and destabilized its client oncoproteins without inducing a heat shock response.

The Enhanced Cytotoxicity on Breast Cancer Cells by Tanshinone I-Induced Photodynamic Effect

[Scientific Reports] The breast cancer cell line MDA-MB-231 was chosen as a model, and the photodynamic effect of Tanshinone I on cancer cells was evaluated by MTT assay and flow cytometry.

Circ_0001982 Aggravates Breast Cancer Development Through the Circ_0001982-miR-144-3p-GSE1 Axis

[Journal Of Biochemical And Molecular Toxicology] A murine xenograft model assay was performed to determine circ_0001982-induced effects on breast cancer cell tumor properties in vivo.

Extracellular Guanosine and Guanine Nucleotides Decrease Viability of Human Breast Cancer SKBR-3 Cells

[Biological & Pharmaceutical Bulletin] Treatment with guanosine or guanine nucleotides increased mitochondrial production of reactive oxygen species, and modified the cell cycle.

Umbilical Cord-Derived Mesenchymal Stem Cells Attenuate S100-Induced Autoimmune Hepatitis via Modulating Th1 and Th17 Cell Responses in Mice

[Stem Cells International] Bone marrow-derived MSCs could exert an immunosuppression effect to ameliorate the S100-induced autoimmune hepatitis model by inhibiting several proinflammatory cytokines and upregulating of PD-L1 in liver tissue.

Dual siRNA-Loaded Cell Membrane Functionalized Matrix Facilitates Bone Regeneration with Angiogenesis and Neurogenesis

[Small] The hybrid cell membrane (MM) loaded small interfering RNA-polyvinylimide (siRP) was synthesized as siRNA@MMs to coat on polylactone electrospun fibers for mimicking the natural bone matrix.

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