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Review

Breast Cancer Organoids Derived from Patients: A Platform for Tailored Drug Screening

[Biochemical Pharmacology] Investigators deliver an overview of breast organoid culture techniques and outline future prospects for organoid modeling.

Bioinspired Multiphase Composite Gel Materials: From Controlled Micro-Phase Separation to Multiple Functionalities

[Chem] The critical design criteria and fabrication strategies of gel materials with micro-phase separation are summarized. Then, the multiple functionalities of these materials are systemically reviewed, including surface engineering, mechanical properties, shape memory, and sensor properties.

Application of Organoids in Regenerative Medicine

[Stem Cells] Scientists review the available applications of organoids in regenerative medicine and the current challenges concerning this field.

Enhancing HCC Treatment: Innovatively Combining HDAC2 Inhibitor with PD-1/PD-L1 Inhibition

[Cancer Cell International] The authors review the application of ideal histone deacetylases 2 (HDAC2) inhibitors with solid anti-tumor efficacy in combination with immunotherapy for HCC.

Impact of Ferroptosis on Preeclampsia: A Review

[Biomedicine & Pharmacotherapy] The authors explore the new therapeutic target of preeclampsia through oxidative stress in ferroptosis.

Beyond Epithelial Damage: Vascular and Endothelial Contributions to Idiopathic Pulmonary Fibrosis

[Journal Of Clinical Investigation] The authors propose that vascular and endothelial cell abnormalities are both causal and consequential in the pathobiology of idiopathic pulmonary fibrosis and that fuller evaluation of dysregulated pathways may lead to effective therapies and a cure for this devastating disease.

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