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Emerging Role of miRNA in Prostate Cancer: A Future Era of Diagnostic and Therapeutics

[Gene] The authors provide a connection between miRNA expression profiles and prostate cancer by elucidating the fundamental processes of miRNA expression and the target genes.

Cardiovascular Human Organ-on-a-Chip Platform for Disease Modeling, Drug Development, and Personalized Therapy

[Journal of Biomedical Materials Research Part A] The authors focus on human organ-on-a-chip systems to model cardiovascular diseases, to perform drug screening, and to advance personalized medicine.

Creating Mini-Pregnancy Models In Vitro with Clinical Perspectives

[Ebiomedicine] The authors review recent achievements in culturing cells from tissues involved in pregnancy; specifically, trophoblasts from the placenta, and more.

FBXW7 in Breast Cancer: Mechanism of Action and Therapeutic Potential

[Journal of Experimental & Clinical Cancer Research] Scientists focus on F-box and WD repeat domain-containing 7 (FBXW7)'s role in a range of breast cancer malignant behaviors and summarize the pertinent cellular targets, signaling pathways, as well as the mechanisms regulating FBXW7 expression.

Autophagy-Targeted Nanoparticles in Breast Carcinoma: A Systematic Review

[Cell Biology International] The authors investigate the potential of free nanoparticles in the induction or inhibition of autophagy and consider this effect on the therapy process in breast carcinoma.

Emerging Oral Drug Options for Ulcerative Colitis

[Expert Opinion On Emerging Drugs] Despite the availability of a variety of therapeutic compounds and improved management strategies, one-third of ulcerative colitis patients with moderate-to-severe disease do not benefit from the existing treatments or experience drug-related side effects. The authors summarize available evidence on oral drugs, which are now being explored in clinical trials or are ready to enter the clinics.

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