Review

[Molecular Medicine] The authors highlighted the link between small ubiquitin-like modifier (SUMO) pathway and lung diseases, especially the sumoylated substrate such as C/EBPα in bronchopulmonary dysplasia, PPARγ in pneumonia, TFII-I in asthma, HDAC2 in COPD, KLF15 in hypoxic pulmonary hypertension, SMAD3 in idiopathic pulmonary fibrosis, and YTHDF2 in cancer.

[Life Sciences] The authors reviewed some fundamental aspects of the most validated protein markers of stemness, autophagy, the mitochondrial function and energy metabolism in oral CSC.

[Life Science Alliance] Recent technological advances have unveiled molecular features that characterize totipotent cells. Single-cell or low-input sequencing technologies allow the dissection of pre- and post-fertilization developmental processes at the molecular level with high resolution.

[Periodontology 2000] New evidence provides a strong impetus to explore heparan sulfate as a potential novel therapeutic agent to treat periodontitis, support alveolar bone maintenance, and promote bone formation.

[Trends In Molecular Medicine] SVEP1 is contained within the extracellular matrix and circulates in plasma, making it a priority candidate for disease diagnostics, prognostics, and therapeutics.

[Trends In Endocrinology And Metabolism] The authors showcase recent studies on the splicing and alternative splicing of key genes in metabolic pathways in the liver, the effect of metabolic signals on the spliceosome, and therapeutic intervention points based on RNA splicing.