Review

[Breast Cancer] Scientists summarize the recent developments on the functional role of miRNAs secreted directly or indirectly from the tumor microenvironment-resident cells in facilitating tumor growth, progression, and metastasis.

[Cell Death & Disease] Scientists review the dual roles that senescence plays in pancreatic ductal adenocarcinoma (PDA) development and progression, the signaling effectors that critically regulate senescence in PDA, the identification and reactivation of molecular targets that control senescence program for the treatment of PDA.

[Expert Review Of Clinical Immunology] The authors provide a comprehensive overview of available clinical trials and real-world data for infliximab (IFX) subcutaneous (SC) treatment of inflammatory bowel disease, focusing on the potential benefits of switching from IFX intravenous to IFX SC.

[MedComm] The authors summarize the current knowledge of CSC markers and stemness regulators in brain tumors.

[Mechanisms Of Ageing And Development] The authors discuss the advances made in the last decade using iPSC technology to study the most common age-associated diseases, including age-related macular degeneration, neurodegenerative and cardiovascular diseases, brain stroke, cancer, diabetes, and osteoarthritis.

[ACS Biomaterials Science & Engineering] The authors explore the exosome–glioblastoma (GBM) interlink, the clinical impact of exosomes on GBM biomarkers, the therapeutics signature of exosomes in GBM, exosome-based research challenges, and future directions in GBM.