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The Immune Function of Dermal Fibroblasts in Skin Defence against Pathogens

[Experimental Dermatology] Scientists discuss the role of dermal fibroblasts in the war against pathogens, as they have important immune functions in anti-infection immunity which should not be overlooked.

Microfluidic-Based Skin-on-Chip Systems for Safety Assessment of Nanomaterials

[Trends In Biotechnology] The authors review current advances in skin-on-chip models and their potential to elucidate biological mechanisms, and discuss strategies to recapitulate skin physiology on-chip, improving control over nanomaterials exposure and transport across cells.

Tumor-Associated Myeloid Cells in Cancer Immunotherapy

[Journal Of Hematology & Oncology] The authors provide an overview of the literature with a focus on the recent research progress evaluating the heterogeneity of tumor-associated myeloid cell (TAMC) origins. They summarize the major therapeutic strategies targeting TAMCs with heterogeneous sources, shedding light on their implications for cancer antitumor immunotherapies.

A Review of Recent Advances in Peptide-Based Anticancer Therapeutic Vaccines and Nanovaccines in Prostate Cancer

[International Journal of Peptide Research and Therapeutics] The authors provide an overview of the immune response, tumor microenvironment, and present level and future trends of expanding prostate cancer immunotherapy.

Lifestyle Interventions in Nonalcoholic Fatty Liver Disease

[Nature Reviews Gastroenterology & Hepatology] Lifestyle interventions, including diet and physical activity, are the main treatments for nonalcoholic fatty liver disease. The Mediterranean diet, or a diet similar in its culturally sensitive components, is the most effective diet for losing weight.

Pharmacotherapies of NAFLD: Updated Opportunities Based on Metabolic Intervention

[Nutrition & Metabolism] The authors summarize the metabolic characteristics of the development of nonalcoholic fatty liver disease (NAFLD), including glucose metabolism, lipid metabolism, and intestinal metabolism, and provide insight into pharmacological targets.

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