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Human Immunology News
Type 2 Immunity in the Brain and Brain Borders
[Cellular & Molecular Immunology] The authors discuss the beneficial and detrimental roles of type 2 immune cells and cytokines in central nervous system injury and homeostasis, cognition, and diseases such as tumors, Alzheimer’s disease and multiple sclerosis.
Human Immunology News
Germinal Center-Dependent and -Independent Immune Responses of Tumor-Infiltrating B Cells in Human Cancers
[Cellular & Molecular Immunology] Investigators highlight the need for more integrative B cell immunology studies to rationally investigate TIL-B cells as a leverage for antitumor therapies.
Human Immunology News
Role of B Cells in Immune-Related Adverse Events Following Checkpoint Blockade
[Immunological Reviews] Scientists focus on the possible role of humoral immunity, specifically human B cell subsets and autoantibodies in the pathogenesis of immune checkpoint blockade-induced immune-related adverse events.
Neural Cell News
Nanoparticles Mediated the Diagnosis and Therapy of Glioblastoma: Bypass or Cross the Blood–Brain Barrier
[Small] Scientists review the application and progress of nanomedicine delivery systems in brain tumors, summarizing the mechanism of nanomaterials crossing the blood-brain barrier. Furthermore, the specific application of nanotechnology in glioblastoma is discussed in depth.
Neural Cell News
The Role of Chromatin Remodeler SMARCA4/BRG1 in Brain Cancers: A Potential Therapeutic Target
[Oncogene] The authors explore the multifaceted interaction between SMARCA4 and various brain cancer types, highlighting its roles in tumor pathogenesis, the pathways it regulates, and the advances that have been made in understanding the functional relevance of mutations.
Cell Therapy News
Neuroprotection of Stem Cells against Ischemic Brain Injury: From Bench to Clinic
[Translational Stroke Research] The authors provide an overview of the advances made in the understanding of the various types of stem cells and progress made in the use of these stem cells for the treatment of ischemic brain injuries.