Review

[Osteoporosis International] The authors review the recent progress of highly purified skeletal stem cells, their function in bone development and repair, and the impact of aging on skeletal stem cells.

[Trends In Cell Biology] The ECM was tightly regulated and dynamically remodeled; this is an important factor for adipose tissue (AT) expansion and can result in modifications to the physical shape and biological function of AT. Investigators focus on ECM remodeling in adipose tissue and how it affects obesity-related cancer progression.

[Immunity] The authors discuss recent progress in understanding how metabolic regulation relates to type 2 immunity firstly by considering specifics of metabolism within type 2 immune cells, and secondly by stressing how type 2 immune cells are integrated more broadly into the metabolism of the organism as a whole.

[Cell] Scientists highlight the biology of anti-tumor immunity underlying response and resistance to immune checkpoint therapy (ICT), discuss efforts to address the current challenges with ICT, and outline strategies to guide the development of subsequent clinical trials and combinatorial efforts with ICT.

[Tissue Engineering Part B-Reviews] The authors introduce representative achievements and challenges in small-caliber tissue-engineered vascular grafts generation using human-induced pluripotent stem cells, and encapsulate the potential solution and future directions.

[Stem Cells] Investigators review recent strategies for promoting in situ tissue regeneration through bone marrow-derived stem cell mobilization or homing in animal models as well as in human trials.