Review

[European Journal Of Haematology] Scientists analyze the kinetic of immune reconstitution among umbilical cord blood, peripheral blood, and bone marrow in hematopoietic stem cell transplant patients by focusing on natural killer cells, B and T lymphocytes, and neutrophils.

[Stem Cell Reviews and Reports] The authors discuss the function of miR-21 in regenerative medicine of the liver, nerve, spinal cord, wound, bone, and dental tissues. In addition, the function of natural compounds and lncRNAs was analyzed as potential regulators of miR-21 expression in regenerative medicine.

[Inflammopharmacology] The authors propose that thalidomide can mitigate inflammation in idiopathic pulmonary fibrosis, and can be repurposed either as monotherapy or in combination with nintedanib and pirfenidone.

[FEBS Journal] Investigators reported on the emerging methods and cutting-edge technologies in 3D cell culture platforms and discuss their potential use in unveiling tumour microenvironmental cues, drug screening and personalized treatment.

[Expert Opinion on Drug Discovery] The authors describe novel model systems and take a thorough overlook of microfluidic chips, synthetic matrices, multicellular systems, bioprinting, and stem cell-derived pancreatic organoid systems.

[Nature Cancer] Scientists outline single-cell analyses in PDAC, discuss their implications on our understanding of the disease and present future perspectives of multimodal approaches.