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Bone Marrow Adipose Tissue: Regulation of Osteoblastic Niche, Hematopoiesis, and Hematological Malignancies

[Stem Cell Reviews and Reports] Recent findings have identified novel progenitor subsets of bone marrow adipocytes recruited during the bone marrow adipogenesis within different skeletal and HSC niches.

Eradicating the Tumor “Seeds”: Nanomedicines-Based Therapies against Cancer Stem Cells

[Daru-Journal Of Pharmaceutical Sciences] The authors summarize the biological hallmarks and markers of CSCs, and the nanotechnology-based therapies to eradicate them.

The Role of Astrocytic α7 Nicotinic Acetylcholine Receptors in Alzheimer Disease

[Nature Reviews Neurology] Investigators discuss the involvement of astrocytic α7nAChRs in the instigation and potentiation of early amyloid-β pathology and explore their potential as a target for future reactive astrocyte-based therapeutics and imaging biomarkers in Alzheimer's disease.

Lost in Local Translation: TDP-43 and FUS in Axonal/Neuromuscular Junction Maintenance and Dysregulation in Amyotrophic Lateral Sclerosis

[Neuron] The authors cover recent discoveries on axonal translation as a critical mechanism for neuronal maintenance/survival. They focus on two RNA binding proteins, transactive response DNA binding protein-43 (TDP-43) and fused in sarcoma (FUS), whose mutations cause amyotrophic lateral sclerosis and frontotemporal dementia.

The Vascular Endothelial Growth Factor (VEGF) System as a Key Regulator of Ovarian Follicle Angiogenesis and Growth

[Molecular Reproduction and Development] The members of the VEGF system affect the proliferation, survival, and migration of endothelial and nonendothelial cells and are involved in the regulation of follicular angiogenesis and development.

Designing Biomimetic Scaffolds for Skin Tissue Engineering

[Biomaterials Science] Scientists review the structure and function of skin tissue and the process of wound healing, and summarize the materials and manufacturing methods used to fabricate skin tissue engineering scaffolds.

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