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Trends in 3D Models of Inflammatory Bowel Disease

[Biochimica Et Biophysica Acta-Molecular Basis Of Disease] Investigators provide a critical overview on the state-of-the-art on existing 3D models of intestinal inflammation and discusses the remaining challenges, providing insights on possible pathways towards achieving IBD mimetic models.

Therapeutic Potential of Oleanolic Acid in Liver Diseases

[Naunyn-Schmiedebergs Archives Of Pharmacology] The authors explore the latest research on the biological effects of oleanolic acid (OA) and its derivatives. They explore the mechanisms of action of these compounds in both in vitro and in vivo research models and, ultimately, highlight OA as a promising candidate for alternative therapies in the treatment and management of chronic liver disease.

Nanotechnology and Bioengineering Approaches to Improve the Potency of Mesenchymal Stem Cell as an Off-the-Shelf Versatile Tumor Delivery Vehicle

[Medicinal Research Reviews] The authors review the preclinical and clinical studies that have evaluated MSCs as a selective tumor delivery tool in various cancer therapy approaches, including gene therapy, immunotherapy, and chemotherapy.

Twenty Years of Islet-on-a-Chip: Microfluidic Tools for Dissecting Islet Metabolism and Function

[Lab On A Chip] The authors explore the various islet-on-a-chip devices used to immobilize islets, regulate the microenvironment, and dynamically detect islet metabolism and insulin secretion.

Roles of Exosomes in Immunotherapy for Solid Cancers

[Cell Death & Disease] Scientists review the composition and sources of exosomes in the solid cancer immune microenvironment and further elaborate on the potential mechanisms and pathways by which exosomes influence immunotherapy for solid cancers.

RNA-Binding Proteins in Breast Cancer: Biological Implications and Therapeutic Opportunities

[Critical Reviews In Oncology/Hematology] Investigators summarize the regulatory mechanisms of RNA-binding proteins (RBPs) and their signaling crosstalk in breast cancer. They emphasize the potential of certain RBPs as prognostic factors due to their effects on proliferation, invasion, apoptosis, and therapy resistance of breast cancer cells.

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