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Induced-Pluripotent Stem Cells and Neuroproteomics as Tools for Studying Neurodegeneration

[Academic Radiology] Investigators highlight studies from the past sive years on the contributions of iPSCs within neuroproteomic investigations, which uncover the molecular mechanisms behind neurodegenerative llnesses.

Inhibitor of PD-1/PD-L1: A New Approach May Be Beneficial for the Treatment of Idiopathic Pulmonary Fibrosis

[Journal Of Translational Medicine] The authors discuss the application of PD-1/PD-L1 checkpoint in idiopathic pulmonary fibrosis, with the aim of finding a new direction for idiopathic pulmonary fibrosis treatment.

The Yin and Yang of Chromosomal Instability in Prostate Cancer

[Nature Reviews Urology] In the context of prostate cancer, studies indicate that chromosomal instability has a key role in disease progression and might also offer a therapeutic vulnerability that can be pharmacologically targeted.

Decoding Leukemia at the Single-Cell Level: Clonal Architecture, Classification, Microenvironment, and Drug Resistance

[Experimental Hematology & Oncology] The authors provide a comprehensive summary of current single-cell studies on leukemia and highlight the markers and mechanisms that show promising clinical implications for the diagnosis and treatment of leukemia.

Progress in Cardiac Tissue Engineering and Regeneration: Implications of Gelatin-Based Hybrid Scaffolds

[International Journal Of Biological Macromolecules] Scientists review state-of-the-art gelatin/GelMA-based hybrid scaffolds currently applied for cardiac tissue engineering and regenerative therapy.

Critical Appraisal of the piRNA-PIWI Axis in Cancer and Cancer Stem Cells

[Biomarker Research] The authors provide an overview of piRNA biogenesis and critically review the evidence for the role of piRNA-PIWI axis in CSCs.

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