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The Yin and Yang of Chromosomal Instability in Prostate Cancer
[Nature Reviews Urology] In the context of prostate cancer, studies indicate that chromosomal instability has a key role in disease progression and might also offer a therapeutic vulnerability that can be pharmacologically targeted.
Hematopoiesis News
Decoding Leukemia at the Single-Cell Level: Clonal Architecture, Classification, Microenvironment, and Drug Resistance
[Experimental Hematology & Oncology] The authors provide a comprehensive summary of current single-cell studies on leukemia and highlight the markers and mechanisms that show promising clinical implications for the diagnosis and treatment of leukemia.
Cell Therapy News
Progress in Cardiac Tissue Engineering and Regeneration: Implications of Gelatin-Based Hybrid Scaffolds
[International Journal Of Biological Macromolecules] Scientists review state-of-the-art gelatin/GelMA-based hybrid scaffolds currently applied for cardiac tissue engineering and regenerative therapy.
Cancer Stem Cell News
Critical Appraisal of the piRNA-PIWI Axis in Cancer and Cancer Stem Cells
[Biomarker Research] The authors provide an overview of piRNA biogenesis and critically review the evidence for the role of piRNA-PIWI axis in CSCs.
Dermal Cell News
Vascularized 3D Human Skin Models in the Forefront of Dermatological Research
[Advanced Healthcare Materials] The authors spotlight the milestones and recent progress in the fabrication and utilization of vascularized skin models, as well as advances including the use of bioreactors, organ-on-a-chip devices, and organoid systems.
Endothelial Cell News
Non-Coding RNAs and Angiogenesis in Cardiovascular Diseases: A Comprehensive Review
[Molecular And Cellular Biochemistry] The authors go through the functions of non-coding RNAs like circular RNAs, and microRNAs as well as long non-coding RNAs in modulating cardiovascular disorders.