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The Yin and Yang of Chromosomal Instability in Prostate Cancer

[Nature Reviews Urology] In the context of prostate cancer, studies indicate that chromosomal instability has a key role in disease progression and might also offer a therapeutic vulnerability that can be pharmacologically targeted.

Decoding Leukemia at the Single-Cell Level: Clonal Architecture, Classification, Microenvironment, and Drug Resistance

[Experimental Hematology & Oncology] The authors provide a comprehensive summary of current single-cell studies on leukemia and highlight the markers and mechanisms that show promising clinical implications for the diagnosis and treatment of leukemia.

Progress in Cardiac Tissue Engineering and Regeneration: Implications of Gelatin-Based Hybrid Scaffolds

[International Journal Of Biological Macromolecules] Scientists review state-of-the-art gelatin/GelMA-based hybrid scaffolds currently applied for cardiac tissue engineering and regenerative therapy.

Critical Appraisal of the piRNA-PIWI Axis in Cancer and Cancer Stem Cells

[Biomarker Research] The authors provide an overview of piRNA biogenesis and critically review the evidence for the role of piRNA-PIWI axis in CSCs.

Vascularized 3D Human Skin Models in the Forefront of Dermatological Research

[Advanced Healthcare Materials] The authors spotlight the milestones and recent progress in the fabrication and utilization of vascularized skin models, as well as advances including the use of bioreactors, organ-on-a-chip devices, and organoid systems.

Non-Coding RNAs and Angiogenesis in Cardiovascular Diseases: A Comprehensive Review

[Molecular And Cellular Biochemistry] The authors go through the functions of non-coding RNAs like circular RNAs, and microRNAs as well as long non-coding RNAs in modulating cardiovascular disorders.

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